■ 학력

2010. 09. ~ 2017. 12. Cornell University, Weill Cornell Medicine, Biochemistry, Cell Biology and Molecular Biology program, 이학박사

2005. 03. ~ 2007. 02. KAIST 화학과, 이학석사

2001. 03. ~ 2005. 02. KAIST 화학과, 이학사

■ 경력

2025. 03. ~ 현재. 조교수, 부산대학교 자연과학대학 화학과

2022. 11. ~ 2025. 02. Senior Research Scientist, Memorial Sloan Kettering Cancer Center

2021. 03. ~ 2022. 11. Research Associate, Memorial Sloan Kettering Cancer Center

2017. 11. ~ 2021. 03. Research Fellow, Memorial Sloan Kettering Cancer Center

2008. 06. ~ 2010. 06. 육군사관학교 교수부 물리화학과 전임강사

2007. 06. ~ 2008. 06. 육군사관학교 교수부 물리화학과 강사

■ 전공분야

막단백질(이온채널 및 수송체)의 물질 수송 메커니즘 

Cryo-EM 및 X-ray 결정학을 이용한 단백질 고해상도 구조 분석

리간드-단백질 상호작용 생화학

■ 연구 논문

1.     S Oh, J Lee, HJ Choi, S Kim, V Sapuru, M Kim and RK Hite. Discovery of selective inhibitors for the lysosomal Parkinson’s disease channel TMEM175, J. Am. Chem. Soc., 2024.8.21.

2.     S Oh, R Stix, W Zhou, JD Faraldo-Gomez and RK Hite. Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175, Proc. Natl. Acad. Sci. USA. 119(44), e2208882119, 2022.10.24.

3.     S Oh, F Marinelli, W Zhou, J Lee, HJ Choi, M Kim, JD Faraldo-Gomez and RK Hite. Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K+ channel, eLife, 11, e75122, 2022.5.24.

4.     M Bitter*, S Oh*, Z Deng, S Rahman, RK Hite and P Yuan. Structure of the Wilson disease copper transporter ATP7B, Sci. Adv., 8, eabl5508, 2022.3.4.

5.     S Oh, N Paknejad and RK Hite. Gating and selectivity mechanism for the lysosomal K+ channel TMEM175, eLife, 9, e53430, 2020.3.31.

6.     DM Kern, S Oh, RK Hite and SG Brohawn. Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs, eLife, 8, e42636, 2019.2.18

7.     S Oh and O Boudker. Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh. eLife, 7, e37291, 2018.9.26.

8.     O Boudker and S Oh. Isothermal titration calorimetry of ion-coupled membrane transporters. Methods, 76, 171-182, 2015.4.1.

9.     G Verdon*, S Oh*, R Serio and O Boudker. Coupled ion binding and structural transition along the transport cycle of glutamate transporters. eLife, 3, e02283, 2014.5.19.

10.   N Reyes, S Oh and O Boudker. Binding thermodynamics of a glutamate transporter homolog. Nat. Struc. Mol. Biol., 20, 634-640, 2013.4.7.

11.   HM Kim*, S Oh*, KJ Lim, J Kasamatsu, JY Heo, BS Park, H Lee, OJ Yoo, M Kasahara and Jie-Oh Lee. Structural diversity of the hagfish variable lymphocyte receptors. J. Biol. Chem., 282(9) 6726-6732, 2007.3.2. 

12.   HM Kim, BS Park, JI Kim, SE Kim, J Lee, S Oh, P. Enkhbayar, N.Matsushima, H Lee, OJ Yoo and Jie-Oh Lee. Crystal structure of the TLR4-MD-2 complex with bound endotoxin
antagonist eritoran. Cell, 130(5), 906 - 917, 2007.9.7. 

https://www.ncbi.nlm.nih.gov/myncbi/secheol.oh.1/bibliography/public/